Soft Condensed Matter Seminar
April 16, 2019 - 3:00pm to 4:00pm
Marcus Nanotechnology Building
Conference Room 1116
Our understanding of how genomes are organized inside the interphase nucleus, and of the molecular factors involved, is rapidly improving. In this talk, first, I will review some of the recent research that has led to this current understanding. However, I will then present a number of results, including measurements of chromatin dynamics in living cells, that challenge aspects of this picture. I will then develop and explore a modified hypothesis for the mechanisms underlying genome organization. Finally, I will compare the consequences of our modified model of chromatin organization to genome-wide experimental data.