Extracting Hidden Hierarchies in Complex Spatial Biological and Physical Network

Extracting Hidden Hierarchies in Complex Spatial Biological and Physical Network

Soft Condensed Matter & Physics of Living Systems

Date

April 26, 2017 -
2:00pm to 3:00pm

Location

HOWEY

Room

S107

Speaker

Affiliation

The Rockefeller University

Natural and man-made transport webs are frequently dominated by dense sets of nested cycles. The architecture of these networks -- the topology and edge weights -- determines how efficiently the networks perform their function. Yet, the set of tools that can characterize such a weighted cycle-rich architecture in a physically relevant, mathematically compact way is sparse. In order to fill this void, this seminar presents a new characterization that rests on an abstraction of the physical `tiling' in the case of a two dimensional network to an effective tiling of an abstract surface in space that the network may be thought to sit in.

 Generically these abstract surfaces are richer than the plane and upon sequential removal of the weakest links by edge weight, neighboring tiles merge and a tree characterizing this merging process results. The properties of this characteristic tree can provide the physical and topological data required to describe the architecture of the network and to build physical models.

This new algorithm can be used for automated phenotypic characterization of any weighted network whose structure is dominated by cycles, such as, for example, mammalian vasculature in the organs, the root networks of clonal colonies like quaking aspen, and the force networks in jammed granular matter. In particular this seminar will also present some progress in the analysis of both neurovasculature and force networks chains.​