Ciliated tissues: structure, mechanics and biological function

Ciliated tissues: structure, mechanics and biological function

Nonlinear Science & Mathematical Physics

Date

March 28, 2018 - 11:00am to 12:00pm

Location

Howey - School of Physics

Room

N110

Speaker

Affiliation

University of Southern California

 Abstract

Motile cilia are hair-like protrusions from epithelial cells that beat collectively to transport fluid.  On the tissue level, cilia serve diverse biological functions, such as mucociliary clearance in the airways and cerebrospinal fluid transport in the brain ventricles. Yet, the relationship between the structure and organization of ciliated tissues and their biological function remains elusive.

Here, I will present a series of models that examine the role of cilia-driven flows in particle transport, mixing, capture and filtering. I will conclude by commenting on the implications of these models to understanding the biophysical mechanisms underlying the interaction of ciliated tissues with microbial partners.